How Do BP-Lowering Drugs work: What are Their Side Effects?

All BP-lowering drugs manipulate our bodies in various ways. The body mechanism generally maintains distribution of blood flow between different organs of the body. Blood pressure can be decreased by lowering the entire blood level in the body, by reducing heart output or by relaxing the spiral muscles and thus widening their bore.

Thus, all BP-lowering drugs operate through one or more of these pathways. However, they may vary in the way they reach them. Some drugs act first on the kidney, some on the brain, some act directly on the small arteries or heart. Thus, the nature of possible side effects depend on which pathways they take.

There are plenty of BP-lowering drugs available today in the market, but the exact knowledge of how these drugs work to reduce blood pressure is still incomplete. For instance, “diuretics” are the second oldest BP-lowering drugs and considered as one of the most effective BP-lowering drugs. However, there is still no proper agreement among scientists and experts. Yes, we understand that diuretics raise the output of sodium, but they also relax small arteries and affect blood volume.

Side effects of BP-lowering drugs:

Almost all BP-lowering drugs have different possible side effects. However, the two main things you need to remember are:

  • There are different possible side effects and this doesn’t mean that they are either severe or inevitable.
  • It is possible to have beneficial, unpleasant side effects

There are two main side effects which are common to all groups of BP-lowering drugs:

* The first one is impotence. All groups of BP-lowering drugs can cause complete or partial failure of erection in men. However, the effect is reversible, it can return to normal function when you stop taking the drugs.

* The second is fainting. But, a few of the drugs can only cause an actual faint or feeling of faintness. It can also happen if the blood pressure is too low because of over treatment.

Fainting occurs due to the sudden fall in blood pressure. When the blood supply to the brain falls below (the required blood flow to maintain consciousness), then faints occur. A feeling of impending blackout, sweating and nausea are some of the warning symptoms before all such faints. Therefore, if you get such warning symptoms, sit down keeping your head down and the faint can be avoided.

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