Cholestrol

Cholesterol Reducing Drugs

Cholesterol reducing drugs are mostly suggested for patients whose levels of cholesterol are too high and cannot be controlled. Important drugs include statins, fibrates, bile acid sequestrates and niacin.

Widely Used Cholesterol Reducing Drugs

Statins:

These are the most widely used drugs for cholesterol treatment. Statins block the synthesis of cholesterol in the body. It inhibits the enzyme HMG Co-A reductase that is vital for synthesis. It prevents clot formation, blockages and heart attack. It is generally recommended when cholesterol levels are too high.

Side effects of statins include muscle pain, liver damage, nausea, headache, stomach upset and vomiting are the most common side effects associated with statin medication.

Bile Acid Sequesters:

These are compounds that bind to bile acids and excrete them in the stools. They prevent bile acids from reaching liver. Due to the presence of less bile acids, liver starts to produce them by using cholesterol. Thereby, reducing cholesterol in the body. Side effects of these drugs include abdominal pain, diarrhea, bloating and deficiency of vitamins A, D, E and K.

Fibrates:

These are medications that help to lower triglycerides in the body. They lower triglyceride production by reducing the production of VLDL’S by the liver. These VLDL particles carry triglycerides in the body. Fibrates speeds up the removal of triglycerides from the body,. They improve the levels of good cholesterol in the body. Headache, stomach pain and dizziness are the side effects of fibrates.

Niacin:

Niacin is effective in reducing LDL levels and improves the good cholesterol levels in the body. The side effects of niacin include inflammation of liver, high glucose levels and indigestion.

Cholesterol absorption inhibitors:

These are compounds that are effective for preventing the uptake of cholesterol from small intestine into circulation. Ezetimibe is the most effective absorption inhibitor. Side effects of these inhibitors include itching, muscle pain, tiredness and stomach upset.

Therefore, taking cholesterol reducing drugs has a positive impact on reduction of cholesterol. But these drugs should be taken moderately to prevent side effects associated with it.

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